产品货号:
Z26149
中文名称:
SIK2抗体
英文名称:
Anti-SIK2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SIK2 Antibody |
指标别名 | QIK,SNF1LK2,LOH11CR1I,KIAA0781,QIK,Qin-induced kinase,SIK-2 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,ICC,IF |
基因名称 | SIK2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | SIK2 antibody was raised against a 16 amino acid synthetic peptide near the center of human SIK2.The immunogen is located within amino acids 270 - 320 of SIK2. |
计算分子量 | 104kDa |
成分 | SIK2 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | SIK2 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Salt-inducible kinase 2 (SIK2),like its closely related homolog SIK1,belongs AMPK subfamily of the Ser/Thr protein kinase family and negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC).SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1 alpha and UCP-1 in brown adipocytes,impairment of which has been implicated in obesity and insulin resistance in human and animal models.SIK2 has also been reported as a key regulator for neuronal survival after ischemia,suppressing CREB-mediated gene expression after oxygen-glucose deprivation. |
Uniprot ID | Q9H0K1 |
基因名全称 | Salt-inducible kinase 2 |
蛋白名全称 | Salt-inducible kinase 2 |
推荐稀释比 | SIK2 antibody can be used for detection of SIK2 by Western blot at 1μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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